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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
18.18
Human Site:
Y277
Identified Species:
33.33
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
Y277
M
N
G
G
D
I
R
Y
H
I
Y
N
V
N
E
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
F273
M
N
G
G
D
L
K
F
H
I
Y
N
L
G
N
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
L86
A
E
Q
H
V
P
A
L
E
L
W
K
D
I
E
Dog
Lupus familis
XP_542675
460
51324
N218
Y
R
D
L
K
P
E
N
V
L
L
D
D
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
Y277
M
N
G
G
D
V
R
Y
H
I
Y
N
V
D
E
Rat
Rattus norvegicus
Q63651
564
63750
Y277
M
N
G
G
D
V
R
Y
H
I
Y
N
V
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
Y277
M
N
G
G
D
I
R
Y
H
I
Y
N
V
S
E
Chicken
Gallus gallus
NP_990026
593
64642
Y307
M
N
G
G
D
L
R
Y
H
V
Y
N
V
D
E
Frog
Xenopus laevis
NP_001087513
575
66421
F273
M
N
G
G
D
L
K
F
H
I
Y
H
M
G
D
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Q191
G
E
L
F
Y
H
L
Q
R
E
R
C
F
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
F396
M
N
G
G
D
L
K
F
H
I
Y
N
M
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
F290
M
N
G
G
D
L
K
F
H
L
Y
N
L
M
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
E499
T
D
Y
M
S
G
G
E
L
F
W
H
L
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
60
6.6
0
N.A.
86.6
86.6
N.A.
93.3
80
53.3
6.6
N.A.
60
N.A.
53.3
N.A.
P-Site Similarity:
100
86.6
20
20
N.A.
100
100
N.A.
100
100
93.3
6.6
N.A.
86.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
8
0
70
0
0
0
0
0
0
8
16
31
8
% D
% Glu:
0
16
0
0
0
0
8
8
8
8
0
0
0
0
54
% E
% Phe:
0
0
0
8
0
0
0
31
0
8
0
0
8
0
0
% F
% Gly:
8
0
70
70
0
8
8
0
0
0
0
0
0
24
16
% G
% His:
0
0
0
8
0
8
0
0
70
0
0
16
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
0
54
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
31
0
0
0
0
8
0
0
8
% K
% Leu:
0
0
8
8
0
39
8
8
8
24
8
0
24
8
0
% L
% Met:
70
0
0
8
0
0
0
0
0
0
0
0
16
8
0
% M
% Asn:
0
70
0
0
0
0
0
8
0
0
0
62
0
8
8
% N
% Pro:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
8
0
0
0
0
39
0
8
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
16
0
0
8
8
0
0
39
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% W
% Tyr:
8
0
8
0
8
0
0
39
0
0
70
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _